First children to participate in European research by UMC Utrecht: Does a single corona vaccine work, too?

Medical Facts Editorial / Janine Padding August 30, 2022 – 07:36

Protecting children from 5 to 11 years old from Corona? UMC Utrecht is investigating whether a single shot of the Pfizer-BioNTech vaccine protects as well as two shots in children with coronavirus. Children who wish to be vaccinated can enroll in this study. Seven-year-old Elsa is the first child who recently participated in the CoVacc study.

Elsa, a fictitious name for reasons of privacy, is a seven-year-old girl who herself wanted to take part in the study. So her mother abandoned her. “She wanted to get involved, she is fascinated by the hospital chain and is always eager to help other children. It is a vaccine that has already been approved, so I haven’t seen any problems.”

Why this research in children at such a young age? Dr. Patricia Brugging, a pediatrician, epidemiologist and lead investigator on the CoVacc study: “When children are vaccinated against corona, they receive two injections as standard. But if you’ve had corona before, you sometimes only get one shot. For children who want to be vaccinated – whether one injection works as well as two. But with the potential for fewer side effects and less stress.”

The CoVacc study is looking at 200 children ages 5 to 11 in Europe, including the Netherlands, to check what really works best: one or two injections.

children record

Children as young as 5 and no more than 11 years old can participate in the CoVacc Study. Parents or guardians can register them. Participation is possible if the child is already infected with corona and has not yet received a corona vaccination, but would like to.

You can register for this study via By registering, no obligation is entered into.

approved corona vaccine

The study uses a pediatric vaccine from Pfizer-BioNTech, which has been approved by the EMA (European Medical Agency). Bruijning: “The standard vaccination schedule for children from 5 years of age provides for two injections of 10 micrograms. However, in some countries, only one injection is given if the children have had coronavirus before and you do not belong to a high-risk group. Give one injection Half the stress is on the child and the parents and is expected to cause fewer side effects, but does it also work well? In order to investigate this, half of the children receive one injection, and the other half receive two. In addition, we want to know how long one or two injections provide protection for young children and whether they provide protection against any new variants of SARS-CoV-2.”

CoVacc is part of the European VACCELERATE project “Pan-European Vaccine Development Network”, creating a network ready to respond to emerging epidemics and increasing the capacity to develop vaccines in Europe. VACCELERATE has received funding from the European Union’s Horizon 2020 Research and Innovation Program under grant agreement No. 101037867.

Medical Facts Editorial / Janine Padding

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